Guillain Barre Syndrome, is a rare yet severe disease that commonly affect the peripheral nervous system. It is a group of autoimmune syndromes consisting of demyelinating and acute axonal degenerating forms of the disease (Newswanger, 2004). It means that Antibody can't barely differ the Antigen, which is supposed to be attacked, and our normal body cells.Therefore, Antibodies attack our cells, in GBS is in peripheral nervous system, and cause damages to the nerves itself. This is often happened after an acute infection.
Damaged myelin (nervous system) caused by autoimmune mechanism.
Gradually the patient will lose his reflexes and leading to complete body paralysis. Paralysis in lower limb and legs are commonly called rubbery legs or tingling and numbness in legs. Afterwards this syndrome travels in upper part of the limb (http://www.guillainbarresyndrome.net/).